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KMID : 0363620110320040068
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Journal of Korean Oriental Medicine
2011 Volume.32 No. 4 p.68 ~ p.74
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The Application of High Performance Thin Layer Chromatography for Herbal Formula Standardization
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Choi Min-Kyung
Kim Hyung-Geug
Wang Jing-Hua
Son Chang-Gue
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Abstract
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Objective : The purpose of this study is to expatiate on high performance thin layer chromatography (HPTLC) as a simple, easy and scientific method for evaluation and standardization of herbal formulae.
Methods: Through retrieving HPTLC application for herbal formulae in the literatures, the current situation of HPTLC application, and potential as well as limitation of HPTLC as a standardization method for multi-herbal drug was studied.
Results: HPTLC is a speedy, inexpensive and well-operable tool for possessing multi-capability on component identification, separation, quantification and purification compared to other methods, such as high performance liquid chromatography (HPLC), gas chromatography (GC).
Conclusions : HPTLC is considered as an available and convenient method for quality control and standardization of multi-herbal drugs. Thereby, this method could be recommended to widely applicate in the traditional Korean medicine.
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KEYWORD
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herbal formula, standardization, high performance thin layer chromatography
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